After configuring the WorkPlace Services Express server to use my Domino LDAP server I noticed that WSE was performing quite slowly. Just moving from one page to the next was taking about 30 - 40 seconds.
Playing around with the Domino LDAP configuration I fixed this problem by setting the LDAP setting to automatically create a Full Text Index of the Domino NAB. Restarting the LDAP server and waiting for the index to be built showed a significant increase in speed in WSE.
I'd also recommend that you check the WebSphere Portal administration settings for LDAP and ensure that it is set to reuse the connection.
I've also gotten the Notes Mail Technical Preview portlet working in WSE. More on how to do that later.